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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q9UQ80
USC-OGP 2-DE database
:
Q9UQ80
Q9UQ80
General information about the entry
View entry in simple text format
Entry name
PA2G4_HUMAN
Primary accession number
Q9UQ80
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Proliferation-associated protein 2G4; AltName: Full=Cell cycle protein p38-2G4 homolog; Short=hG4-1; AltName: Full=ErbB3-binding protein 1;.
Gene name
Name=PA2G4
Synonyms=EBP1
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1172
:
pI=6.39; Mw=46315
SPOT OGP-1173
:
pI=5.91; Mw=45157
Cross-references
UniProtKB/Swiss-Prot
Q9UQ80; PA2G4_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
PA2G4_HUMAN
Primary accession number
Q9UQ80
Secondary accession number(s)
O43846 Q9UM59
Sequence was last modified on
January 23, 2007 (version 3)
Annotations were last modified on
March 15, 2017 (version 174)
Name and origin of the protein
Description
RecName: Full=Proliferation-associated protein 2G4; AltName: Full=Cell cycle protein p38-2G4 homolog; Short=hG4-1; AltName: Full=ErbB3-binding protein 1;
Gene name
Name=PA2G4
Synonyms=EBP1
Encoded on
Name=PA2G4; Synonyms=EBP1
Keywords
3D-structure
;
Acetylation
;
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Nucleus
;
Phosphoprotein
;
Reference proteome
;
Repressor
;
Ribonucleoprotein
;
RNA-binding
;
rRNA processing
;
Transcription
;
Transcription regulation
;
Translation regulation
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
U59435; AAB91536.1
; -; mRNA
EMBL
U87954; AAD00646.1
; -; mRNA
EMBL
AF104670; AAD05561.1
; -; Genomic_DNA
EMBL
AF104668; AAD05561.1
; JOINED; Genomic_DNA
EMBL
AF104669; AAD05561.1
; JOINED; Genomic_DNA
EMBL
BC001951; AAH01951.1
; -; mRNA
EMBL
BC007561; AAH07561.1
; -; mRNA
EMBL
BC069786; AAH69786.1
; -; mRNA
CCDS
CCDS8902.1; -. [Q9UQ80-1]
; .
RefSeq
NP_006182.2; NM_006191.2. [Q9UQ80-1]
; .
UniGene
Hs.524498; -
; .
UniGene
Hs.745109; -
; .
PDB
2Q8K; X-ray
; 1.60 A; A=2-394
PDB
3J2I; EM
; 11.90 A; A=1-394
PDBsum
2Q8K; -
; .
PDBsum
3J2I; -
; .
ProteinModelPortal
Q9UQ80; -
; .
SMR
Q9UQ80; -
; .
BioGrid
111075; 106
; .
DIP
DIP-31275N; -
; .
IntAct
Q9UQ80; 57
; .
MINT
MINT-5000754; -
; .
STRING
9606.ENSP00000302886; -
; .
MEROPS
M24.973; -
; .
iPTMnet
Q9UQ80; -
; .
PhosphoSitePlus
Q9UQ80; -
; .
SwissPalm
Q9UQ80; -
; .
BioMuta
PA2G4; -
; .
DMDM
13632817; -
; .
SWISS-2DPAGE
Q9UQ80; -
; .
EPD
Q9UQ80; -
; .
PaxDb
Q9UQ80; -
; .
PeptideAtlas
Q9UQ80; -
; .
PRIDE
Q9UQ80; -
; .
DNASU
5036; -
; .
Ensembl
ENST00000303305; ENSP00000302886
; ENSG00000170515. [Q9UQ80-1]; .
GeneID
5036; -
; .
KEGG
hsa:5036; -
; .
UCSC
uc001sjm.4; human. [Q9UQ80-1]
; .
CTD
5036; -
; .
DisGeNET
5036; -
; .
GeneCards
PA2G4; -
; .
HGNC
HGNC:8550; PA2G4
; .
HPA
CAB011711; -
; .
HPA
CAB012428; -
; .
HPA
HPA016484; -
; .
MIM
602145; gene
; .
neXtProt
NX_Q9UQ80; -
; .
OpenTargets
ENSG00000170515; -
; .
PharmGKB
PA32877; -
; .
eggNOG
KOG2776; Eukaryota
; .
eggNOG
COG0024; LUCA
; .
GeneTree
ENSGT00530000063220; -
; .
HOGENOM
HOG000168207; -
; .
HOVERGEN
HBG053117; -
; .
InParanoid
Q9UQ80; -
; .
OMA
THEVYAM; -
; .
OrthoDB
EOG091G0B89; -
; .
PhylomeDB
Q9UQ80; -
; .
TreeFam
TF300010; -
; .
Reactome
R-HSA-6798695; Neutrophil degranulation
; .
SIGNOR
Q9UQ80; -
; .
ChiTaRS
PA2G4; human
; .
EvolutionaryTrace
Q9UQ80; -
; .
GeneWiki
PA2G4; -
; .
GenomeRNAi
5036; -
; .
PRO
PR:Q9UQ80; -
; .
Proteomes
UP000005640; Chromosome 12
; .
Bgee
ENSG00000170515; -
; .
CleanEx
HS_PA2G4; -
; .
ExpressionAtlas
Q9UQ80; baseline and differential
; .
Genevisible
Q9UQ80; HS
; .
GO
GO:0035578; C:azurophil granule lumen
; TAS:Reactome; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005576; C:extracellular region
; TAS:Reactome; .
GO
GO:0030529; C:intracellular ribonucleoprotein complex
; IEA:UniProtKB-KW; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0005730; C:nucleolus
; IDA:UniProtKB; .
GO
GO:0005634; C:nucleus
; IDA:MGI; .
GO
GO:0003677; F:DNA binding
; IDA:MGI; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:0003700; F:transcription factor activity
; sequence-specific DNA binding; IDA:MGI
GO
GO:0031625; F:ubiquitin protein ligase binding
; IPI:UniProtKB; .
GO
GO:0007050; P:cell cycle arrest
; TAS:ProtInc; .
GO
GO:0008283; P:cell proliferation
; TAS:ProtInc; .
GO
GO:0043066; P:negative regulation of apoptotic process
; ISS:UniProtKB; .
GO
GO:0045892; P:negative regulation of transcription
; DNA-templated; IDA:MGI
GO
GO:0043312; P:neutrophil degranulation
; TAS:Reactome; .
GO
GO:0045597; P:positive regulation of cell differentiation
; ISS:UniProtKB; .
GO
GO:0006417; P:regulation of translation
; IEA:UniProtKB-KW; .
GO
GO:0006364; P:rRNA processing
; IEA:UniProtKB-KW; .
GO
GO:0006351; P:transcription
; DNA-templated; IEA:UniProtKB-KW
Gene3D
1.10.10.10; -
; 1; .
Gene3D
3.90.230.10; -
; 2; .
InterPro
IPR004545; PA2G4
; .
InterPro
IPR000994; Pept_M24
; .
InterPro
IPR018349; Pept_M24A_MAP2_BS
; .
InterPro
IPR011991; WHTH_DNA-bd_dom
; .
Pfam
PF00557; Peptidase_M24
; 1; .
SUPFAM
SSF46785; SSF46785
; 1; .
SUPFAM
SSF55920; SSF55920
; 2; .
TIGRFAMs
TIGR00495; crvDNA_42K
; 1; .
PROSITE
PS01202; MAP_2
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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